Blood proteins may help to track the pathological progression of Lewy body disease

Early detection of Alzheimer’s disease-related changes in Parkinson’s disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins. Researchers at Nagoya University in Japan have also discovered that the blood levels of neurofilament light chain (NfL) protein are elevated at an early stage of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). This discovery may provide a method to identify potential patients and to make early interventions. The findings were published in npj Parkinson’s Disease.

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