Clinical trial shows improved survival with blinatumomab in B-cell precursor leukemia subtype

Clinical trial shows improved survival with blinatumomab in B-cell precursor leukemia subtype

A significant survival improvement finding for adults with newly diagnosed BCR::ABL1-negative B-cell precursor acute lymphoblastic leukemia appears in the New England Journal of Medicine. The practice-changing finding is from the randomized phase 3 study E1910, which evaluated blinatumomab immunotherapy in patients who were in remission and tested negative for measurable residual disease (MRD) after an initial round of chemotherapy.

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